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Risk of Renal Dysfunction in Schistosoma haematobium Infected Patients

Author Affiliations

  • 1Department of Medical Laboratory Science (Chemical Pathology Option), Faculty of Basic Medical Sciences, College of Health Sciences, Niger Delta University, Wilberforce Island, P.M.B. 071, Bayelsa State, Nigeria
  • 2Department of Medical Laboratory Science (Chemical Pathology Option), Federal Medical Centre, Yenagoa, Bayelsa State, Nigeria
  • 3Department of Medical Laboratory Science (Medical Microbiology/Parasitology Option), Faculty of Basic Medical Sciences, College of Health Sciences, Niger Delta University, Wilberforce Island, P.M.B. 071, Bayelsa State, Nigeria

Res. J. Recent Sci., Volume 5, Issue (5), Pages 1-3, May,2 (2016)

Abstract

Schistosoma haematobium is a parasitic infection considered by World Health Organization (WHO) as a significant public health problem, second to malaria among parasitic diseases that occurs frequently in Africa and Middle East. This study was aimed at assessing the risk of renal dysfunction in patients infected with Schistosoma haematobium in Yenagoa, Nigeria. Blood specimens were collected from thirty subjects infected with Schistosoma haematobium and another thirty subjects with no evidence of Schistosoma haematobium infection (control) into non anticoagulated (plain) bottles, these specimens were allowed to clot, spun and the serum obtained used for the quantitative measurement of the following biochemical parameters using spectrophotometer S23A model: creatinine, urea, protein and uric acid. The results showed higher statistical significant differences (p<0.05) of creatinine and urea with mean values of 1.83mg/dl and 86.68mg/dl respectively in the Schistosoma haematobium infected subjects as against the mean values of 0.80mg/dl and 20.20mg/dl respectively in the control subjects while protein showed lower statistical significant differences (p<0.05) with a mean value of 48.27g/l in the Schistosoma haematobium infected subjects as against a mean value of 71.53 g/l in the control subjects. However, the uric acid mean value of 247.25Ámol/l in the Schistosoma haematobium infected subjects was not statistically different (p>0.05) from the mean value of 247.20Ámol/l in the control subjects. In conclusion, the significant differences of the mean values of these biochemical parameters in the Schistosoma haematobium infected subjects as compared with that of the control subjects show that they are at risk of renal dysfunction. The estimation of these serum biochemical parameters in all cases of Schistosoma haematobium infection is therefore recommended.

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