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Antimicrobial Activity of root extract of Phyllanthus fraternus Webster: An Ethnomedicinal plant

Author Affiliations

  • 1Mehsana Urban Institute of Science, Ganpat University, Kherwa, Dist. Mehsana, North Gujarat, INDIA
  • 2M.G. Science Institute, Dadasaheb Mavlankar Campus, Navarangpura, Ahmedabad, Gujarat, INDIA

Res. J. Recent Sci., Volume 3, Issue (ISC-2013), Pages 275-278, (2014)

Abstract

Phyllanthus fraternus Webster, a pan tropical weed originated from western India, belongs to family Euphorbiaceae and commonly known as “Bhumyamlaki”. It is a medicinally very useful plant species which is frequently used by tribal of Gujarat to cure certain diseases like asthma, cough, diarrhea, diabetes, skin diseases and scabies. Current study is targeted the on the activity of antimicrobial metabolites from the root. Root were dried and extracted by methanol. This root extract of Phyllanthus fraternus was screened against eleven clinically important bacterial strains and three antifungal strain by disc diffusion method. Result showed maximum antibacterial activities against P.aeruginosa with zone of inhibition of 25 mm followed by S. typhiB with a zone of inhibition of 11 mm and minimum against S. typhi Awith zone of inhibition of 10 mm. Similarly the maximum antifungal activity was noted against A. niger (10 mm). Absolute methanol was used as control during the experiments. This indicates that antimicrobial activities may be due to presence of secondary metabolites. Hence, the plant can be used to discover bioactive natural products that may serve as leads in the development of new pharmaceuticals research activities. As the antimicrobial work has been not carried out so far on Phyllanthus fraternus,

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