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A Novel Method to Quantify the Nucleophilicity of Dihydroxy Benzoic Acid Regioisomers by Polarography

Author Affiliations

  • 1Department of Chemistry, Nowrosjee Wadia College, affiliated to SPPU, Pune 411 001, India
  • 2Department of Chemistry, Nowrosjee Wadia College, affiliated to SPPU, Pune 411 001, India
  • 3Department of Chemistry, Nowrosjee Wadia College, affiliated to SPPU, Pune 411 001, India
  • 4Department of Chemistry, Nowrosjee Wadia College, affiliated to SPPU, Pune 411 001, India
  • 5Department of Chemistry, Nowrosjee Wadia College, affiliated to SPPU, Pune 411 001, India

Res.J.chem.sci., Volume 6, Issue (12), Pages 56-58, December,18 (2016)

Abstract

The reduction propensities of 2,6-dihydroxy benzoic acid (2,6-DBA) and 3,5-dihydroxy benzoic acid (3,5-DBA) in aqueous medium using classical polarography have been studied to portray their reactivity in aromatic substitution reactions in terms of their relative nucleophilicity. The half-wave reduction potentials for 2,6-DBA and 3,5-DBA have been found to be 800 and 900 mV respectively indicating lower nucleophilicity for 2,6-DBA than that of 3,5-DBA. These results have been confirmed from complementary data by kinetic studies for the iodination of these two regioisomers. This two-pronged complementary study assesses the reactivity of the two substrates in a quantitative manner.

References

  1. Berliner E. (1966)., The Current State of Positive Halogenating Agents., J.Chem. Edu., 43(3), 124‐133.
  2. Bonde S.L., Dangat V.T., Borkar V.T. and Yadav R.P. (2012)., Rapid Iodinations of Xylidines in Aqueous Medium: Kinetic Verification of Speculated Reactivities., Res.J.Chem.Sci., 2(6), 1‐5.
  3. Bashir W, Borkar V.T. and Dangat V.T. (2015)., A Quantitative Assessment of the Nucleophilicity of Cytocine in Aqueous Solution by Polarography Complemented by Hydrodynamic Voltammetry., Oriental J. of Chem., 31(4), 2421-2425.
  4. Borkar V.T. and Dangat V.T. (2014)., Structure-Reactivity Correlation of Thiophene and Thiophene -2- Sulfonic Acid by Investigation of Rapid Kinetics of Bromination in Aqueous Medium., Res.J.Chem.Sci., 4(2), 48‐51.
  5. Bashir W., Borkar V.T. and Dangat V.T. (2016)., Rapid Bromination Study of Nuclebase-Uracil in Aqueous Medium by Hydrodynamic Voltammetry., Asian Journal f Chemistry, 28(8), 1871-1872.