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Metal Complexes of Quinoxaline Derivatives: Review (Part-II)

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Author Affiliations

  • 1Department of Chemistry, University College of Engineering, Nagercoil, Anna University Constituent College, Nagercoil 629004, Tamil Nadu, INDIA

Res.J.chem.sci., Volume 5, Issue (4), Pages 64-84, April,18 (2015)

Abstract

Over the past decades, there is increasing information about synthesis, characterization and applications of metal complexes including quinoxaline derivative metal complexes. The focus of the review is emphasized on synthesis, characterization, structural analysis, theoretical calculations and biological studies of quinoxaline derivative metal complexes. These types of review provide unique platform for systematically studying the various quinoxaline derivative metal complexes synthesized so far and their characterizations. We have also highlighted the synthetic strategies developed to synthesize metal complexes. Several characterizations which are not covered in part-I like CD-spectroscopy are also included in this review paper. This review is also a focus of the reports on the structural aspects that the quinoxaline based ligands plays on compounds reported in last seven years. Furthermore in this review the current progress of research in the field of quinoxaline derivative metal complexes from 2007 to end of 2014 is summarized. The structure was confirmed by single crystal x-ray diffraction studies. An overview of application of quinoxaline derivative metal complexes is also presented. Structural elucidation using Density Functional Theory (DFT) and Time Dependent-Density Functional Theory (TD-DFT) are included. In addition to various biological studies included in the previous part, cytotoxicity, photo cytotoxicity studies, anti-tubercular studies, insulin mimetic activity, anti-trypanosome cruzi activity, anti-proliferative activities are included.

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