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Azole Drug : A Novel Inhibitor for Corrosion

Author Affiliations

  • 1Department of Science and Humanities, Christian College of Engineering and Technology, Oddanchatram, Dindigul, Tamil Nadu, INDIA
  • 2 Head, Department of Chemistry, APA College for Women, Palani, Dindigul, Tamil Nadu, INDIA
  • 3 Department of Chemistry, APA College of Arts and Culture, Palani Dindigul, Tamil Nadu, INDIA

Res.J.chem.sci., Volume 5, Issue (2), Pages 11-16, February,18 (2015)

Abstract

Heterocyclic compounds with atoms like N, O, and S are good corrosion inhibitors for metals and alloys. Molecules containing both N and S have good inhibition property when compared with molecules containing only N or S. A good inhibitor of corrosion should be alkaline. Azole drugs such as Fluconazole, Ketoconazole and Clotrimazole are good corrosion inhibitors due to the presence of aromatic rings, hetero-atoms and alkaline character. The rate of corrosion and inhibition efficiency of mild steel in the absence and presence of Fluconazole (FA) and Zn2+ containing 60ppm chloride ion has been studied by mass loss method. The inhibition efficiency of the system with 220ppm FA and 50ppm Zn2+ was high. AC impedance spectra, polarization study, Fourier Transform Infra Red spectra were analysed for knowing the nature of protective coating formed.

References

  1. Lashgari M., Arshadi M. and Biglar M., Chem. Eng. Comm., 197, 1303-1314 (2010)
  2. Bentiss F., Traisnel M. and Lagrenee M., Corros. Sci., 42, 127-146 (2000)
  3. Trabanelli G., Chemical Industries: Corrosion Mechanism”, F.Mansfeld (Ed.), New York, MarcelDekker, P.120 (1987)
  4. Yan Y., Li W., Cai L. and Hou B., Electrochim. Acta 53,5953-5960 (2008)
  5. Derya Loce H., Kaan C., Emregul and Atakol O., Corrosion Sci., 50, 1460-1468 (2008)
  6. Bentiss F., Lgrenee M., Traisnel M. and Hornez J.C., Corros. Sci., 41, 789-803 (1999)
  7. Riggs O.L. Jr., Corrosion Inhibitors, Ed. C. C. Nathan, USA, NACE, 7, (1973)
  8. Pattan S.R., Dighe N.S., Merekar A.N., Laware R.B., Shinde H.V. and Musmade D.S., AsianJ. Res. Chem., (2), 196-201 (2009)
  9. Ramesh S. and Rajeswari S., Corrosion Inhibition of mild steel in neutral aqueous solution by new Triazole derivatives, Electrochimicat Acta, 49(5), 811-820 (2004)
  10. Bentiss F., Lagrene’e M., Traisnel M. and Gorenez J., The Corrosion Inhibition of Mild steel in acidic media by a new Traizole Derivative, Corrosion Sci., 41(4), 789-803 (1999)
  11. Bentiss F., Traisnel M., Gengembre L. and Lagrene’e M., A new Triazole Derivative as Inhibitor of the acid corrosion of mild steel, Electrochemical studies, weight loss determination, SEM AND XPS, Applied surface Science, 152(3-4), 237-249 (1999)
  12. Sudheer and Quraishi M.A., Effect of pharmaceutically active compound Omeprazole, on the corrosion of mild steel in hydrochloric acid solution, J. Chem. Pharm. Res, 3(5), 82-92 (2011)
  13. Manohar S.E., Environmental Chemistry (London, Sixth Edition, Lewis Publishers, (1996)
  14. www.doctorfungus.org/thedrugs/fluconazole.php, (2014)
  15. Ahamad I., Khan S., Ansari K.R., Quraishi M.A., J .Chem. Pharm. Res., 3, 703-717 (2011)
  16. Rajendran S., Uma V., Krishnaveni A., Jeyasundari J., Shyamaladevi B. and Maivannan M., Arabian, J. Sci. Eng., 34, 147-158 (2010)
  17. Rajendran S., Sumithra P., Devi B.S. and Jeyasundar J., Zastita Materijala,50, 223 (2009)
  18. Rathish R.J., Rajendran S., Christy J.L., Devi B.S., Johnmary S., Manivannan M., Rajam K., Rengan P., Open Corros. J., 3, 38-44 (2010)
  19. Benita Sherine M., Mani R.K. and Rajendran S., J. Electrochem, Soc. India, 57, 67-73 (2008)
  20. Narayanasamy B. and Rajendran S., Prog. org. coat., 67,246-254 (2010)
  21. Yesu Y., Thangam M., kalanithi C., Mary Anbarasi and Rajendran S., The Arabian J. Sci. Eng., 34, 37- 47 (2009)
  22. Kanimozhi S.A. and Rajendran S., Arabian J. Sci. Eng., 35, 41-52 (2009)
  23. Sathiyabama J., Rajendran S., Sundari J.J. and Shyamaladevi B., J. Eng. Sci. Tech. Rev., 3, 27-31 (2010)
  24. Silverstein R.M., Bassler G.C. and Morrill T.C., Spectometric Identification of Organic Compound, John wiley sons, Newyork, 134 (1986)
  25. Sekine I., Hirakawa Y., Corrosion,42, 272 (1986)