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Rapid and Economic Synthesis of Schiff Base of Salicylaldehyde by Microwave Irradiation

Author Affiliations

  • 1Dept. of Industrial Chemistry, St. Xavier’s College, Navarangpura, Ahmedabad, Gujrat, INDIA
  • 2Loyola Centre for Research and Development, Ahmedabad, Gujrat, INDIA

Res.J.chem.sci., Volume 3, Issue (10), Pages 97-99, October,18 (2013)

Abstract

Schiff base synthesis is usually acid-catalyzed and usually require refluxing the mixture of aldehydes (or ketone) and amine in organic medium. However, assistance of microwave irradiation for synsthesis of schiff base is introduced now a day. In the present study microwave promoted condensation reaction of salicylaldehyde and p-amino phenol are displayed. The method was also compared with conventional method for determination of production efficiency and production economic. Characterization of these Schiff base were done by TLC and IR spectra. From the study, it was concluded that the microwave irradiation method is very rapid, reliable and economic method for production of schiff base.

References

  1. Ashraf M.A., Mahmood K., Wajid A., Maah M.J. and Yusoff I., Synthesis, Characterization and Biological Activity of Schiff Bases, International Conference on Chemistry adn Chemical Process, 10, 1-7 (2011)
  2. Bader N.R., Applications of Schiff’S Bases Chelates in Quantitative Analysis : A Review Nabil Ramadan Bader. RASAYAN Journal of Chemistry 3, 660-670 (2010)
  3. Aslam M., Anis I., Afza N., Noreen Z. and Iqbal L., Antibacterial and Lipoxygenase (LOX) Inhibitory activities of 2-[(2- methoxybenzylidene) amino] phenol derivatives. Molecular and Clinical Pharmacology 4, 26-31 (2013)
  4. Vaqas M., et al. Salicylaldehyde Salicyloylhydrazone-A short Review. Science International 25, 85-89 (2013)
  5. Kumar N. and Sharma P., Synthesis of New Schiff-Base Complexes and Their Applications. Internation Journal of Applied Research and study 2, 1-6 (2013)
  6. Somani R., et al. Optimization of Microwave Assisted Synthesis of some Schiff Bases. International Journal of ChemTech Research 2, 172-179 (2010)
  7. Kulshrestha A. and Baluja S., Microwave Promoted Synthesis of Some Schiff Bases. Scholars Research Library 2, 221-224 (2010)
  8. Yang Z. and Sun P., Compare of three ways of synthesis of simple Schiff base. Molbank 12-14 (2006)
  9. Satyanarayana V.S.V., Sreevani P., Sivakumar A. and Vijayakumar V., Synthesis and antimicrobial activity of new Schiff bases containing coumarin moiety and their spectral characterization. Arkivoc, 221-233 (2008)