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Synthesis and Structural Studies on Some Transition metal complexes of Bis-(benzimidazole-2-thio) ethane, propane and butane ligands

Author Affiliations

  • 1Department of Chemistry, College of Science, University of Mosul, Mosul, IRAQ

Res.J.chem.sci., Volume 2, Issue (6), Pages 43-49, June,18 (2012)

Abstract

Transition metal complexes of Co(II),Ni(II),Cu(II) and Zn(II) with the tetradentate ligands [L1= 1,2-bis-(benzimidazole-2-thio) ethane, L2=1,3-bis-(benzimidazole-2-thio) propane, L3=1, 4-bis-(benzimidazole-2-thio)butane], derived from the condensation of 2-mercaptobenzimidazole and 1,2-dibromoethane or 1, 3-dibromo propane or 1, 4-dibromobutane were synthesized. Characterization has been done on the basis of analytical conductance, magnetic data, infrared, electronic spectra , metal content analysis and 1HNMR data for the ligands. From analytical data the stoichiometry of the complexes has been found to be (1:1) (metal: ligand). IR spectra data suggest that the ligands behave as bidentate with N,N or S,S or S,S,N,N donor sequence toward the metal ions. On the basis of the above spectral, physicochemal, data as well as magnetic moment measurements tetrahedral and square planner geometries were assigned for the complexes.

References

  1. Hyappa P.B., Young J.K., Moore J.S. and Suslic K.S. Dendrimer-Metalloporphyrins:Synthesis and CatalysisJ.Am. Chem. Soc., 118, 5708 (1996)
  2. Castillo-Blum S.E. and Barba-Behrens N.,chemistry of some biologically active ligands, Chem. Rev., (3), 196 (2000)
  3. Mohan G., and Rajesh N., Synthesis and antiactivity of N-Pyridinobenzamide-2-carboxylic acid and its metal chelates, Indian J.Pharm, 24, 207 (1992)
  4. Kong D., Reibenspies J., Mao J. and Clearfield A., 30-membered octaazama- crocyclic ligand: synthesis, characterization, thermodynamic stabilities andcleavage activity of homodinuclear copper and nickel complexesInorg. Chim. Acta, 342, 158 (2003)
  5. Pawar N.S., Dalal D.S., Shimpi S.R. and Mahulikar P.P.,Studies of microbial activity of N-alkyl and Nthiazolyl)-1H-benzimidazoles, Eur. J.Pharm. Sci.(2004)
  6. Özden S., Atabey D., Yildiz S. and H.Göker, and Potent Antimicrobial activity of Some Novelor Ethyl 1H-Benzimidazole-5-carboxylates derivatives carrying amide or amidine, Bioorg.Med. Chem(2005)
  7. Ören I., Temiz Ö., Yalcin I., Sener E. and Altanlar N., Synthesis and antimicrobial activity of some novel 2,5and/or 6-substituted benzoxazole and benzimidazolederivativesEur. J.Pharm. Sci., 153(1998)
  8. He Y., Ww B., Yang J., Robinson D., Risen L., Ranken R., Blyn L., Sheng S.and Swayze E.E.,biological evaluations of novel benzimidazoles as potential antibacterial agents, Bioorg.Med.Chem.Lett.(2003)
  9. .Ayhan-Kilcigil G. and Altanlar N.,antifungal properties of some benzimidazole derivatives, Turk.J.Chem., 30, 223 (2006)
  10. Yoe-Reyes F.J., Bernes S. and BarbaDichlorobis (1benzimidazoleCrystallog. E61, m875 (2005)
  11. Sahin E., Ide S., Kurt M. and Yurdakul S., investigation of dibromo bis (benzimidazole) Zn(II) complexJ.Mol. Struc., 616, 259 (2002)
  12. Sahin E., Ide S.,M.Kurt and Yurdakul S., Structural investigation of dichlorobis (benzimidazole)complex, Z.Kristallogr, 218,385 (2003)
  13. Tellez F.H., Sandoral L., CastilloBehrens N.,Coordination behavior of benzimidazole,2substituted benzimidazoles and benzothiazoles, towards transition metal ions, ARKIVOC,245 (2008)
  14. Gervy J.M., Tellez F., Bernes S., Nöth H., Contreras R. and Barba-Behrens N., Synthesis and characterization of new cis-[PtCl(isopropylamine)(amine)] compounds: cytotoxic activity and reactions with 5with their trans-platinum isomers532 (2002)
  15. Tellez F., Barba-Behrens N., Flores-Parra A. and Contreras R., Coordination behavior of benzimidazole, 2-substituted benzimidazoles and benzothiazoles, towards transition metal ions, Polyhedron, 22, 2481 (2004)
  16. Matthews C.J., Clegg W., Heath S.L., Martin N.C., Stuart M.N. and Lockhart J. C., Coordination of Zn(II),Cd(II)andAg(I) by Bis (benzimidazole) Ligands, Hg(II) Inorg. Chem., 37(2),199 (1998)
  17. Buttrus N.H., AL-Smaan S.H. and AL-Asalli S.M., Mono-di-and trinuclear complexes of Co(II),Ni(II),Cu(II) and Zn(II) with 1,4-bis(sodiumthioglycolate) butane, Internation. J. Chem., 20(1), 37 (2010)
  18. Abdalrazaq E.A., Buttrus N.H. and Abd AL-Rahman A.A. M.,Synthesis and characterization of gold (III) complexes with bis-(1,4-sodium thioglycolate) butane ligand, Asian J.Chem., 22(3), 2179 (2010)
  19. Abdalrazaq E.A., Buttrus N.H., AL-Kattan W.T., Jbarah A.A. and AL-Matarneh M., Reaction of Pd+2 and Pt+2 with pyrrolidinedithio carbamate and cysteine ligands: Synthesis and DFT calculations, J. Sulfur, Chem., 32(2),159 (2011)
  20. Vogel A.I., A text Book of Quantitative Inorganic Analysis Including Elementary Instrumental Analysis,461 (1967)
  21. Geary W.J., The use of conductivity measurements in organic solvents for characterization of coordination compounds, Coord.Chem.Rev. , 8 (1971)
  22. Kulkarni P.A., Habib I.S., Saraf V.D. and Deshpande M.M., Synthesis, spectral analysis and antimicrobial activity of some new transition metal complexes derived from 2, 4-dihydroxy acetophenons, Res. J. Pharm. Biol. Chem. Sci., 3, 107 (2012)
  23. Buttrus N.H.Synthesis of new disultam niobium(V) and disultam Zinc (II) complexes using disultam mercury compounds, Asian J.Phys.,, 104 (1997)
  24. Mostafa M.,Metal Chelates of Hydrazone Ligand Chelating Tendencies of 2-Carboxy-phenylhydrazoacetoacetanilide (2-Cphaaa) Ligand, Res.J. Chem.Sci., 1(7),1-4 (2011)
  25. Manav N., K.Mishra A. and Kaushik N.K., Triphenyl phosphine adducts of platinum (IV) and palladium(II) dithiocarbamates complexes: a spectral and in vitro study, Spectro. Chim.Acta Part A, 60, 3087(2004)
  26. Chaudhary R. and Shelly, Synthesis, Spectral and Pharmacological Study of Cu(II), Ni(II) and Co(II) Coordination Complexes. Res.J. Chem.Sci., 1(5),1-5(2011)
  27. Neelama M., Rao P.V. and E-Anuradha G.H.Synthesis and structural studies on transition metal complexes derived from 4-hydroxy-4-methyl-2-pentanone-1H- benimidazole-2yl-hydrazone, J.Chem., 8(1), 29 (2011)
  28. Hussein S.S.,Mostafa M.,Stefan S.L. and Abdel-Aziz E., Structural Diversity of 3d Complexes of an Isatinic Quinolyl Hydrazon Res.J. Chem.Sci. 1(5),67-72 (2011)
  29. Buttrus N.H. and Mohammed S.I., Structural diversity of 3d complexes of an istinic quinolyl hydrazone, Mu'tah Lil-Buhuth Wad-Driasat (Jordon), 19(3), 7(2004)