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Microwave Mediated Dearylation of 2-Aryloxy-5-Nitropyridine

Author Affiliations

  • 1Department of Medicinal Chemistry, Piramal Life Sciences Limited, 1Nirlon Complex, Goregaon East, Mumbai 400063, INDIA

Res.J.chem.sci., Volume 1, Issue (6), Pages 84-87, September,18 (2011)

Abstract

2-aryloxy-5-nitropyridine derivatives exhibited ether cleavage reaction on treatment with alcohols/amines in presence of base like K2CO3, Cs2CO3, NaOH, t-BuOK, etc. under microwave irradiation to yield corresponding phenols and 5-nitro-2-substituted pyridine.

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