Antioxidant Potentialities of 4-Acyl isochroman-1,3-Diones
Author Affiliations
- 1Lab. de Chimie Bio-Organique et Phytochimie, UFR-SEA, Université de Ouagadougou, 03 BP 7021 Ouagadougou 03, Burkina FASO
- 2Lab. de Biochimie and Chimie Appliquées, UFR-SVT, Université de Ouagadougou, 09 BP 848 Ouagadougou 09, Burkina FASO
- 3Lab. de Spectrométries et Dynamique Moléculaire Université de Provence, Case 252, Centre de saint Jérôme, Avenue Escadrille Normandie, Niemen 13397, Marseille Cédex 20, FRANCE.
Res.J.chem.sci., Volume 1, Issue (5), Pages 88-90, August,18 (2011)
Abstract
A new family of compounds (4-acyl isochroman-1,3-diones), demonstrating antioxidant properties, have been synthesized and described. Their antioxidant properties are studied herein. These antioxidant characters increased with the electronic withdrawing character of the acyl substituent. So, 4-p-Cyanobenzoyl isochroman-1,3-dione and 4-p-Nitrobenzoyl isochroman-1,3-dione have been found to exhibit a reducing power and to scavenge the DPPH free radical using FRAP and DPPH assays.
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