International E-publication: Publish Projects, Dissertation, Theses, Books, Souvenir, Conference Proceeding with ISBN.  International E-Bulletin: Information/News regarding: Academics and Research

Synthesis and Biological activity for 4-methoxyphenyl (pyrazin-2-yl) methanone and its Detection by GC-MS Techniques

Author Affiliations

  • 1Dept. of Physics, SN Arts, DJM Commerce and BNS Science College, Sangamner, Ahmednagar, Pin– 422605 INDIA
  • 2PDF Applied research and Development Institute, Ahmednagar, Maharashtra INDIA

Res.J.chem.sci., Volume 1, Issue (5), Pages 85-87, August,18 (2011)

Abstract

The synthesis of 4-methoxyphenyl (pyrazin-2-yl) methanone and its detection by GC-MS technique by p-methoxybenzaldehyde reacted with pyrazin-2-yl in the presence of suitable solvent in different conditionto form p-methoxybenzaldehyde. The structure detected with GC-MS and the compound identified with T.L.C. technique and then examined for antibacterial activity.

References

  1. Anzai K., Isono K., Okuma K. and Suzuki S., antibiotics, questiomycins A and B., 125-132, (1960)
  2. Hollstein U., Spectroscopic analysis of theand kinetic DNA binding propertiesactinomycin analogs, Chem. Rev., 74,625-652 (1974)
  3. ButenandtA.Biekert E., Kubler H.,Pigments in the pupal integuments of twoof cabbage white butterfly, Physiol Chem.256 (1960)
  4. Lalehzari A., Desper J. and Levy C.J., Synthesis, crystal structures, and antibacterial activities of two copper(II) complexes derived from 1-[(2-ylethylimino) methyl]-naphthalen- 2-ol transition metal chemistry, Inorg. Chem., 47, 1120 (2008)
  5. Yamaguchi T., Sato K., Izumi R., Tomoda A. and Tohoku J., In Vitro antibacterial activity of Phx-3 elicobacter pyloriiwata, J. Exp.Med., 200,161-165 (2003)
  6. Uruma T., Yamaguchi H., Fukuda M., Kawakami H., Goto H., Kishimoto T., Yamamoto Y., Tomoda A. and Chlamydia pneumoniae resists antibiotics Med. Microbiol., 541143-1149 (2005) Kadzewski A. and Gdaniec M., Phenazine-diamine–water, Acta Cryst., E62,03498-03500 (2006)
  7. Kadzewski A. and Gdaniec M., Phenazine naphthalene-1,5-diamine water, Acta Cryst., E62, 03498-03500 (2006)
  8. Ziegler J., Schuerle T., Pasierb L., Kelly C., Elamin Wright D. W., Self- assembled synthesis, characterization and antimicrobial activity (II) salicylaldimine complexes,Inorg. Chem.,39, 3731(2009)
  9. Leese C.L. and Rydon H.N., Polyazanaphthalenes, Some derivatives of 1:4:5-triazanaphthalene and J. Chem. Soc., Part I, 303 (1955)
  10. Arun V.,Sridevi N., Robinson P.P., Manju S. and K.K.M., Ni(II) and Ru(II) Schiff base complexes as catalysts for the reduction of benzene, J. 304(1-2), 191 (2009)
  11. Dyke S.F., Floyd A.J., Sainsbury M. and Theobald R. S., Organic spectroscopy – An Introduction, Penguin Harmondsworth, London, 249-262 (1971)