International E-publication: Publish Projects, Dissertation, Theses, Books, Souvenir, Conference Proceeding with ISBN.  International E-Bulletin: Information/News regarding: Academics and Research

Efficacy of Unani Formulations Majoon Aqrab and Sharbat Alu Balu in the Management of Nephrolithiasis

    , , , ,

Author Affiliations

  • 1Regional Research Institute of Unani Medicine, Hazratbal, Srinagar, Jammu and Kashmir, INDIA

Int. Res. J. Medical Sci., Volume 3, Issue (7), Pages 24-27, July,28 (2015)

Abstract

The present study was carried out to evaluate the efficacy of Majoon Aqrab and Sharbat Alu Balu in nephrolithiasis. It was an open non-comparative clinical study. 30 patients of both sexes in different age groups were included in this study. A thorough history was taken and clinical examination on baseline and during follow ups were done. Abdominal radio imaging (KUB) and ultrasound were also done at the baseline and at the time of completion of therapy. There was improvement in all symptoms with reduction of size of stones and also disappearance of stones were noted. Therefore it was seen that it is clinically safe in the management of nephrolithiasis.

References

  1. Davidson’s Principles and Practice of Medicine. XVII Edi, London, 461, (1999)
  2. Zakaria Razi, Kitab-Al-Hawi, New Delhi: CCRUM, 10(129), (865-925) (2002)
  3. Shenoy KR., Manual of surgery, II Edi, New Delhi: CBS publishers and Distributors, 617-618, (2005)
  4. Stoilova I, Krastanov A, Stoyanova A, Denev P and Gargova S., Antioxidant activity of a ginger extract Zingiber officinale), Food Chemistry, 102(3), 764-770 (2007)
  5. Vutyavanich T, Kraisarin T and Ruangsri R., Ginger for nausea and vomiting in pregnancy: randomized, double-masked, placebo-controlled trial, Obstet Gynecol, 97(4), 577-582 (2001)
  6. Habib SH, Makpol S, Abdul Hamid NA, Das S, Ngah WZ and Yusof YA., Ginger Extract (Zingiber Officinale) has anti-cancer and anti-inflammatory effects on ethionine-induced hepatoma rats, Clinics, 63(6), 807-813 (2008)
  7. Funk JL, Frye JB, Oyarzo JN and Timmermann BN., Comparative Effects of Two Gingerol-Containing Zingiber officinale extracts on experimental rheumatoid arthritis, J Nat Prod., 72(3), 403-407 (2009)
  8. Carrasco FR, Schmidt G, Romero AL, Sartoretto JL, Caparroz-Assef SM and Bersani-Amado CA et al, Immuno modulatory activity of Zingiber officinale Roscoe, Salvia officinalis L. and Syzygium aromaticum L. essential oils: evidence for humor- and cell-mediated responses, J Pharm Pharmacol, 61(7), 961-967 (2009)
  9. Lakshmi BVS and Divya V., Antiurolithiatic and antioxidant activity of Zingiber officinale rhizomes on ethylene glycol-induced urolithiasis in rats, Int J Adv Pharmacy Med Bioallied Sci,2(3), 148-153 (2014)
  10. Faridi P, Roozbeh J and Mohagheghzadeh A., Ibn-Sina's life and contributions to medicinal therapies of kidney calculi, Iran J Kidney Dis., 6(5), 339-345 (2012)
  11. Gomes A, Bhattacharjee P, Mishra R, Biswas AK, Dasgupta SC and Giri B., Anticancer potential of animal venoms and toxins, Indian journal of experimental biology,48, 93-103 (2010)
  12. Khan M and Siddiqui M., Antimicrobial activity of Piper fruits, Nat prod Rad, 6(2), 111-113 (2007)
  13. Samykutty A, Shetty AV, Dakshinamoorthy G, Bartik MM, Johnson GL, Webb B and Zheng G et al, Piperine, a Bioactive Component of Pepper Spice Exerts Therapeutic Effects on Androgen Dependent and Androgen Independent Prostate Cancer Cells, PLoS One, 8(6), e65889 (2013)
  14. Agbor GA, Akinfiresoye L, Sortino J, Johnson R and Vinson JA., Piper species protect cardiac, hepatic and renal antioxidant status of atherogenic diet fed hamsters, Food Chem, 134(3), 1354-1359 (2012)
  15. Bang JS, Oh da H, Choi HM, Sur BJ, Lim SJ and Kim JY et al, Anti-inflammatory and antiarthritic effects of piperine in human interleukin 1beta-stimulated fibroblast-like synoviocytes and in rat arthritis models, Arthritis Res Ther, 11(2), R49 (2009)
  16. Sharma S, Kalia NP, Suden P, Chauhan PS, Kumar M and Ram AB. et al., Protective efficacy of piperine against Mycobacterium tuberculosis, Tuberculosis(Edinb), 94(4), 389-396 (2014)
  17. Saha S and Verma RJ., Polyphenolic extract of Piper nigrum inhibits sodium oxalate induced oxidative stress in rat kidney, Toxico Envir Health Sci., 6(3), 164-169 (2014)
  18. Ali S, Unani Advia Mufarrada, Tarqi Urdu Beeru New Delhi, (1993)
  19. Kusar A, Zupancic A, Sentjurc M and Baricevic D., Free radical scavenging activities of yellow gentian (Gentiana lutea L.) measured by electron spin resonance, Hum Exp Toxicol., 25(10), 599-604 (2006)
  20. Mathew A, Taranalli A.D. and Torgal SS., Evaluation of anti-inflammatory and wound healing activity of Gentiana lutea rhizome extracts in animals, Pharmaceutical Biology, 42(1), 8-12 (2004)
  21. 1.Oztürk N, Herekman-Demir T, Oztürk Y, Bozan B and Baer KH., Choleretic activity of Gentiana lutea ssp. symphyandra in rats, Phytomedicine, 5(4), 283-288 (1998)
  22. Jasem E and Javdan N., Study of analgesic activity of methanolic extracts of Physalis Alkekengi in adult rats, Pharmacologyonline, , 768-772 (2011)
  23. Helvaci S, Kökdil G, Kawai M, Duran N, Duran G and Güvenç A., Antimicrobial activity of the extracts and physalin D from Physalis alkekengi and evaluation of antioxidant potential of physalin D, Pharm Biol., 48(2), 142-150 (2010)
  24. Laczko-Zold E, Zupko I, Rethy B, Csedo K and Hohmann J., Antioxidant activity of the fruits and hydrophilic compounds of Physalis alkekengi, Acta Pharm Hung.,79(4), 169-173 (2009)
  25. Dornberger K., The potential antineoplastic acting constituents of Physalis alkekengi L. var franchetii Mast, Pharmazie,41(4), 265-268 (1986)
  26. Ji L, Yuan Y, Luo L, Chen Z, Ma X and Ma Z et al., Physalins with anti-inflammatory activity are present in Physalis alkekengi var. franchetii and can function as Michael reaction acceptors, Steroids, 77(5), 441-447 (2012)
  27. Naseri GKM, Maryam M and Gharibnaseri Z., Antispas-modic effect of Physalis alkekengi fruit extract on rat uterus, Iranian J Reprod Med., 6(4), 193-198 (2008)
  28. Montaserti A, Pourheydar M, Khazaei M and Ghorbani R., Anti-fertility effects of Physalis alkekengi alcoholic extract in female rat, Iranian J Reprod Med., 5(1), 13-16 (2007)
  29. Sharma N, Bano A, Dhaliwal HS and Sharma V., Perspectives and possibilities of indian species of genus physalis (l.): A comprehensive review, EJPMR, 2(2), 326-353 (2015)
  30. Ferretti G, Neri D and Bacchetti T., Effect of Italian sour cherry (Prunus cerasus L.) on the formation of advanced glycation end products and lipid peroxidation, Food and Nutrition Sciences, , 1568-1576 (2014)
  31. Jacob RA, Spinozzi GM, Simon VA, Kelley DS, Prior RL and Hess-Pierce B. et al. Consumption of cherries lowers plasma urate in healthy women, J Nutr, 133(6), 1826-1829 (2003)
  32. Kuehl KS, Perrier ET, Elliot DL and Chesnutt JC., Efficacy of tart cherry juice in reducing muscle pain during running: a randomized controlled trial, J Int Soc Sports Nut, 7(1), 17 (2010)
  33. Wang H, Nair MG, Strasburg GM, Chang YC, Booren AM and Gray JI et al. Antioxidant and anti-inflammatory activities of anthocyanins and their aglycon, cyanidin, from tart cherries, J Nat Prod, 62(2), 294-296 (1999)