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Critical assessment of the concept of Mizaj-e-advia (Temperament of Drugs) and its role in Drug development

Author Affiliations

  • 1Dept ofPharmacology, National Institute of Unani Medicine, Kottigepalya, Magadi Road, Bangalore-560091, INDIA
  • 2 Dept of PSM, Kashmir Tibbia College Hospital and Research Centre, Srinagar, Jammu and Kashmir, INDIA

Int. Res. J. Medical Sci., Volume 1, Issue (9), Pages 10-14, October,28 (2013)


The concept of Mizaj-e-advia (temperament of drugs) in Unani medicine is not only unique in its own way of describing the properties of drug substances but also stands the test of time by proving extremely valuable in predicting the behavior of drugs on administration or topical application to humans. Mizaj-e-advia is a broad concept, which describes the pharmacological properties of crude drugs derived from plant, animal and mineral sources. This classical way of drug development may show promising results as an alternative to the extremely cumbersome and costly experimental phase of the conventional drug development process. However, it needs extensive research to unravel its yet obscure pharmacological correlations and scientific interpretations. This work reviews the concept of Mizaj-e-advia and assesses its role in drug developmental process in Unani Medicine. It also includes a review of some important research works so far undertaken in this field, lays emphasis, and highlights certain preferred and important areas for carrying out further research in this direction.


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