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Preliminary Phytochemical Sereening and in Vitro antioxidant Activity of Extracts of whole Plant of Sonchus Oleraceus Asteraceae

Author Affiliations

  • 1Department of Pharmacy, S.V.Govt. Polytechnic College, Bhopal, MP, INDIA L.M. College of Science and Technology Pharmacy Wing, Jodhpur, INDIA

Res. J. of Pharmaceutical Sci., Volume 3, Issue (3), Pages 1-12, March,30 (2014)

Abstract

Plant drug are being increasingly utilized to treat a wide variety of clinical diseases many oxidative stress related diseases are as a result of free radical in body. A lot of research are going on worldwide directed towards natural antioxidant of herbal origin. The Present study was conducted to ascertain the folkloric claim of its antioxidant protential of Crude powdered drug extracted with petroleum ether and ethanol (90%) named as PEX and ALX. Preliminary photochemical screening revealed the presence of cardiac glycoside, steroid, tannis, phenolic compound, flavonoid and carbohydrate. As these compounds are known to support antioxidant acivities hence Further DPPH, H assay and OH-scavenging activity of LX and PEX showed IC-50 as 38.37 g/ml, 52.27 g /ml, 55.27 g/ml, 202.79g/ml, 203.85g/ml respectively our findings provide evidences that the crude extracts of the plant is a potential source of natural antioxidants and this justified its uses in folkloric medicines.

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