Synthesis and Physico-Chemical Analysis of 3-{[(3, 4-Dimethoxy-Phenyl)-Phenylamino-Methyl]-Amino}-2-Phenyl-Quinazolin-4(3h)-One
Author Affiliations
- 1Department of Pharmaceutical Chemistry CMJ University, Shillong, Meghalaya, INDIA
- 2 Narayana Pharmacy College, Chinthareddypalem, Nellore, Andhra Pradesh, INDIA
Res. J. of Pharmaceutical Sci., Volume 1, Issue (2), Pages 26-28, October,30 (2012)
Abstract
Medicinal chemistry as practiced encompasses both definitions, but finding the biochemical pathways through which drug exert their beneficial effects has become a dominating activity of the medicinal chemist and biologist while searching for ahead on a new drug or doing research on a pre-clinical drug candidate. Heterocyclic chemistry is the branch of chemistry dealing with the synthesis, properties, and applications of heterocyclics. Heterocyclic chemistry comprises at least half of all organic chemistry research worldwide. In particular, heterocyclic structures form the basis of many pharmaceutical, agrochemical and veterinary products. Quinazolinone has been considered as a magic moiety possessing myriad spectrum of medicinal activities. Diversity of biological response profile has attracted considerable interest of several researchers across the globe to explore this skeleton for its assorted therapeutic significance. By using different synthetic methods new quinazolinone derivatives were synthesized and characterized by physic-chemical analysis. Quinazolinone is a lead nucleus for future developments to get effective compounds.
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