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Impact of Chelating agent (Zinc) on Heavy metal (Arsenic) caused variations of Hexokinase in different Brain regions of fresh water Teleosts

Author Affiliations

  • 1Dept. of Zoology, Jawaharlal Nehru P.G. College Shyamala Hills-462002, Bhopal, MP, INDIA
  • 2Department of Zoology (DESM) Regional Institute of Education (NCERT), Shyamla Hills-462002 Bhopal, MP, INDIA
  • 3Veena Vadini Ayur. College and Hospital, Kolar Road-462042, Bhopal, MP INDIA

Int. Res. J. Environment Sci., Volume 2, Issue (11), Pages 61-64, November,22 (2013)

Abstract

In the present study the author intend to study the sub-lethal and lethal effect of arsenic separately and in presence of chelating agent zinc on bio-chemical compartmentation of hexokinase, in various brain regions (cerebrum, diencephalon, cerebellum and medulla oblongata) in three phylogenetically and ontogenetically different fish species i.e. Labeo rohita (Ham) Clarias batrachus (Linn) and Channa punctatus (Bloch) under acute studies from a tropical environment.

References

  1. Pathak Neelam B. and Mankodi P.C.,Hydrological status of Danteshwar pond, Vadodora, Gujrat, India, International Research J. of Environment Science, 2(1), 43-48 (2013)
  2. Gautam A., Ecology and pollution of mountain water, A case study of Bhagirathi River, Ashish Publishing House New Delhi(2009)
  3. Farombi E.O, Adelowo O.A. and Ajimolco Y.R.,Biomorkers of oxidative street and heavy metal levels as indicators of environmental pollution in African Cat fish(Clarias garithepinus) from Nigeria Ogum river, Int. J. Env. Res. Pub.Health,158-165 (2007)
  4. Banerjee P., Bhattacharya S.S., Bhattacharjee N., Pathak S., Belon P. and Khuda-Buksh A.R., Ascorbic acid combats arsenic-induced oxidative stress in mice liver, Ecotox. Environ. Safe, 72, 639-649 (2009)
  5. Modi M., Uma Pathak, Kiran Kalia and Flora S.J.S., Arsenic antagonism studies with monoisoamyl DMSA and zinc in male mice, Environ. Toxicol. Pharmacol, 19, 131-132 (2005)
  6. Bolognin S., Drago D., Messori L. and Zatta P., Chelation therapy for neurodegenerative diseases, Med.Res.Rev,29(4), 547-570 (2009)
  7. Flora S.J.S., Bhadauria S., Pant S.C. and Dhakad R.K., Arsenic induced blood and brain oxidative stress and its response to some thiol chelators in rats,Life Sci., 77(18), 2324-2337 (2005)
  8. Finney D.T.,Probit Analysis Method,2nd Edi. Camp. Uni. Press, (1971)
  9. Cappllini M.D., Best Pract. Res. Clin. Haematol.,Iron - Chelating therapy with the new oral agent ICL670 (Exjade), Best Pract. Res.Clin.Haematol., 18, 289-298 ( 2005)
  10. Colowick S.P. and Kaplon N.O.,Methods in Enzymology,XLI (B) Aca. Press. New York, (1975)
  11. Edmonds J.S. and Francesconi K.A., Arsenic in sea foods: Human health aspect and regulations,Marine Pollution, 26, 665-674 (1993)
  12. Farombi E.O, Adelowo O.A. and Ajimolco Y.R., Biomorkers of oxidative street and heavy metal levels as indicators of environmental pollution in African Cat fish (clarias garithepinus) from Nigeria Ogum riverInt. J.Env. Res. Pub. Health, 158-165 (2007)
  13. Gupta R. and Flora S.J.S., The Therapeutic value of Hippophaerhamnoides against sub-chronic arsenic toxicity in mice, J. Med. Food, 8, 353-361 (2005)
  14. Gupta R. and Flora S.J.S., Photother. Res.,Protective value of Aloe vera against some toxic effects of arsenic in mice, Photother. Res., 19, 23-28 (2005)
  15. Hellmich H.L., Eidson K., Cowart J., Crookshanks J., Boone D.K., Shah S., Uchida T., DeWitt Douglas and Prough D.S., Chelation of neurotoxic zinc levels does not improve neuron-behavioral outcome after traumatic brain injury, Neurosci. Lett., 440(2), 155-159 (2008)
  16. Kosnett M.J.,Chelation for heavy metals (arsenic, lead and mercury): Protective or perilous, Clin. Pharmacol. Ther88(3), 412-415 (2010)
  17. Ku Y. and Peters R.W., The effect of weak chelating agents on the removal of heavy metals by precipitation processes, Environ. Progress, 5(3), 147-153 (2006)
  18. Mishra M. and Jain S.K.,Effect of natural ion exchanger chabazite for remediation of lead toxicity ;An experiment study in teleost fish Heteropneustes fossilis, Asian J.Exp Sci, 23(1), 39-44(2009)
  19. Palaniappan PL.RM., Krishna kumar N. and Vadivelu M., Bioaccumulation of lead and the influence of chelating agents in Catla catla fingerlings, Environ. Chem.Lett.,7, 51-54 (2009)
  20. Raibole M. and Singh Y.P., Concentration of heavy metals (copper and lead) in Channa punctatus and Wallago attuwith special reference to upper lake of Bhopal, Biom. & Pharm. J., 4(1), 213-217 (2011)
  21. Shaffi S.A. and Kakaria V.K.,Comparison of the sub lethal effect of metal mixture on gluconeogenic enzyme compartmentations and recovery in brain of three freshwater teleosts, J.Cell and Tissue Res,14-15 (2006)
  22. Shaffi S.A., Manohar Y. and Nandan M.J., Influence of protective agents on metal induced respiratory distress in Labeo rohita, Bul.Env. Cont. Toxicol, 66, 611-616 (2001)
  23. Shaffi S.A., Prakash B.V.B.S., Nichat A. and Raibole M., Microbes as antidote to detoxify the metal caused toxicity in some fresh water teleosts, Nat. Sem. on New Horizons in Toxicol. & substenance of life, 64 (2007)
  24. Rauf A., Javed M., Ubaidullah M. and Abdullah S.,Assessment of heavy metal in sediments of river, Pakistan. Int. J.Agric. and Biology, 11,(2), 197-200 (2009)
  25. Shaffi S.A.,Influence of sub-lethal HCH on differential distribution of dehydrogenase, glycogen, pyruvate & lactate in different brain region in Labeo rohita (Ham).,Indian J. Exp. Biol. 48, 151-157 (2001)
  26. Shaffi S.A. and Habibulla M., 1977 Differential distribution of glycogen, lactate & pyruvate in different brain regions of rat, Indian J.Exp.Biol., 14, 307-308 (2001)
  27. Tandy S., Bossart K., Mueller, Ritschel J., Hauser L., Schulin R. and Nowack B., Extraction of heavy metals from soils using bio-degradable chelating agents, Environ. Sci. Technol, 38 (3),937-944 (2004)
  28. Wenger K., Tandy S. and Nowack B., Effects of chelating agents on trace metal speciation and bioavailability, Biogeo. Chem. Chelating Agents,12, 204-224 (2005)