Antagonistic profiling and phytochemical analysis of roots of Curculigo orchioides and Curcuma angustifolia against UTI bacterial isolates
- 1Dept. in Microbiology, Manonmaniam Sundaranar University, Tirunelveli Rd, Abishekapatti, Tamil Nadu
- 2Dept. in Microbiology, Malankara Catholic College, Mariagiri, Tamil Nadu, India
Int. Res. J. Biological Sci., Volume 9, Issue (3), Pages 25-28, August,10 (2020)
The present study was performed with an aim of determining the phytochemical constituents and antagonistic effect of roots of Curculigo orchioides (family Amaryllidaceae) and Curcuma angustifolia (family Zingiberaceae). Antagonistic effect was evaluated against four UTI causing bacterial isolates by well diffusion method. The results of the study showed, in comparison with Curcuma angustifolia, the root extracts of Curculigo orchioides exhibited higher antagonistic activity against the tested isolates. Also the phytochemical investigation of Curculigo orchioides indicated the presence of phenols, amino acids, glycosides, alkaloids, tannins, terpenoids and coumarins. This study derives in a conclusion that root extracts of Curculigo orchioides can be used to develop antagonistic agents against bacterial isolates causing UTI.
- Stamm, W.E. and Norrby, S.R. (2001)., Urinary tract infections: disease panorama and challenges., The Journal of Infectious Diseases, 183, 1-4.
- Nicolle, L.E. (2008)., Uncomplicated urinary tract infection in adults including uncomplicated pyelonephritis., Urol. Clin. North Am., 35, 1-12.
- Lane, D.R. and Takhar, S.S. (2011)., Diagnosis and management of urinary tract infection and pyelonephritis., Emergency medicine clinics of North America, 29, 539-552.
- Hancock, R.E.W. (2005)., Mechanisms of action of newer antibiotics for Gram-positive pathogens., Lancet. Infect. Dis., 5(4), 209-218.
- Noumedem, J.A.K., Mihasan, M., Lacmata, S.T., Stefan, M., Kuiateand, J.R. and Kuete, V. (2013)., Antibacterial activities of the methanol extracts of ten Cameroonian vegetables against Gram-negative multidrug-resistant bacteria., BMC Complement. Altern. Med., 13(1), 26.
- Middleton, J.R., Fales, W.H. and Luby, C.D. (2005)., Surveillance of Staphylococcus aureus in veterinary teaching hospitals., J. Clin. Microbiol., 43(6), 2916-2919.
- Mahmood, A.M., Doughari, J.H. and Ladan, N. (2008)., Antimicrobial screening of stem bark extracts of Vitellaria paradoxa against some enteric pathogenic microorganisms., Afr. J. Pharm. Pharmacol., 2(5), 089-094.
- Eisenberg, D.M., Kessler, R.C., Foster, C., Norlock, F.E., Calkins, D.R. and Delbanco, T.L. (1993)., Unconventional medicine in the United States., N. Engl. J. Med., 328(4), 246-252.
- Dhar, M.L., Dhar, B.N., Dhawan, D.N. and Mehrota, C.R. (1968)., Screening of Indian plants for biological activity part 1., Indian J. Expt. Biol., 6(6), 232-249.
- Raghunathan, S. and Mitra, R. (1982)., Pharmacognosy of Indigenous drugs., Vol.I, New Delhi.
- Dhenuka, S., Balakrishna, P. and Anand, A. (1999)., Indirect organogenesis from the leaf explants of medicinally important plant Curculigo orchioides Gaertn., J Plant Biochem Biotech, 8, 113- 115.
- Joy, P.P., Thomas, J., Samuel, M. and Skaria, B.P. (2004)., Curculigo orchioides: A plant for health care., Indian J. Areca nut, Spices & Med Plants, 6(4), 131-134.
- Chopra, R.N., Nayar, S.L. and Chopra, I.C. (1956)., Glossary of medicinal plants., CSIR, New Delhi, pp 84.
- Santapou, H. and Henery, A.N. (1976)., A dictionary of the flowering plants in India., New Delhi, CSIR.
- Srivastava, A.K., Srivastava, S.K. and Syamsundar, K.V. (2006)., Volatile composition of Curcuma angustifolia Roxb. rhizome from central and southern India., Flavour and Fragrance Journal, 21, 423-426.
- Sharma, A. (2012)., Traditional processing of Shotti (Curcuma augustifolia Roxb.)-a rhizome based ethnic weaning food., Indian Journal of Traditional Knowledge, 11(1), 154-155.
- Nadkarni, A.K. (1976)., Indian Materia Medica., 3rd edn, Popular Prakashan Pvt. Ltd, I, pp 413.
- Bapalal, G. (1985)., Nighantu Adarsha., Chaukhambha Bharati Academy, Varanasi, pp 579.
- Doble, B., Dwivedi, S., Dubey, K. and Joshi, H. (2011)., Pharmacognostical and antimicrobial activity of leaf of Curcuma angustifolia Roxb., International Journal of Drug Discovery and Herbal Research, 1(2), 46-49.
- Elias, L., Pradeep, Harini, A. and Hegde, P.L. (2015)., Curcuma angustifolia Roxb (Tavaksheeri): A Review., Journal of Pharmacognosy and Phytochemistry, 4(2), 241-243.
- Nayak, S., Jena, A.K. and Sucharita, S. (2013)., In vitro bioactivity studies of wild Curcuma angustifolia rhizome extract against (Hela) Human Cervical Carcinoma cells., World Journal of Pharmacy and Pharmaceutical Sciences, 2(6), 4972 - 4986.
- Shukla, A.C., Pandey, K.P., Mishra, R.K., Dikshit, A. and Shukla, N. (2011)., Broad spectrum antimycotic plant as a potential source of therapeutic agent., Natural Product Journal, 4, 42-50.
- Quamar, M.F. and Bera, S.K. (2014)., Ethno-medico-botanical studies of plant resources of Hoshangabad district, Madhya Pradesh, India: Retrospect and Prospects., Journal of Plant Science & Research, 1(1), 101.
- Parez, C. (1990)., An antibiotic assay by agar well diffusion method., Acta Biol Med Exp., 15, 113-115.
- Yadav, M., Chatterji, S., Gupta, S.K. and Watal, G. (2014)., Preliminary phytochemical screening of six medicinal plants used in traditional medicine., Int. J. Pharm. Pharm. Sci, 6, 539-542.
- Dey, B. and Raman, S.M.V. (1957)., Laboratory Manual of Organic Chemistry., S. Viswanathan publication, Madras.
- Ashok, K.K., Narayani, Subanthini and Jayakumar, (2011)., Antimicrobial Activity and Phytochemical Analysis of Citrus Fruit Peels -Utilization of Fruit Waste., International Journal of Engineering Science and Technology, 3, 5414-5421.
- Dey, P.M. and Harborne, J. B. (1987)., Methods in Plant Biochemistry., Academic Press; London.