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Protective role of Murraya Koenigii and Citrus Medica leaf extract in Thyroxine treated Female Mice

Author Affiliations

  • 1Department of Microbiology, MLB College, Bhopal, MP, INDIA

Int. Res. J. Biological Sci., Volume 4, Issue (4), Pages 22-24, April,10 (2015)

Abstract

The effects of Murraya koenigii and Citrus medica leaves extract were studied to understand the interaction between the two extract in female mice model by using L-thyroxine. The analysis was done by using similar dose but the comparison was made with the response of individual plant extract. Serum level of T and T was increased by the oral administration of L-thyroxine (0.5mg/kg b.w) in albino mice to make them hyperthyroidic. However simultaneous administration of Murraya koenigii (83% and 7.6%) and Citrus medica (73% and 54%) reduce serum T and T level suggested that Citrus medica strongly suppress the serum level of thyroid hormones. These observations explain the hidden potential of the leaves extract in the regulation of thyroid hormones.

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