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Autophagy: Molecular Insight and Role in Plant Programmed Cell Death and Defense Mechanism.

Author Affiliations

  • 1School of Life Sciences, B. S. Abdur Rahman University, Vandalur, Chennai-600048 (TN), INDIA

Int. Res. J. Biological Sci., Volume 4, Issue (2), Pages 78-83, February,10 (2015)

Abstract

Autophagy is an evolutionary conserved pathway of vacuolar degradation of cytoplasmic constituents. The characteristic feature of the pathway is double membrane bound autophagosome which transfer the damaged and excessive cell components to the lysosome or vacuoles for degradation and recycling. Autophagy allows the cell to survive under nutrient starvation and various biotic and abiotic stresses. The molecular mechanism of autophagy has been studied in yeast to mammals and also in plants. Many Experimental results suggested that the basic molecular mechanism and pathways are conserved in yeast, mammals and plants to a large extent. This review highlights basic molecular autophagy and its role in defense mechanism and programmed cell death in plants.

References

  1. Zhuang X. and Jiang L.,Autophagosome biogenesis in plants: roles of SH, Autophagy,10(4), 704-705 (2014)
  2. Zhou L., Zhao J., Guo W. and Zhang T., Functional Analysis of Autophagy Genes via Agrobacterium-Mediated Transformation in the vascular wilt fungus verticilliumdahlia, Journal of Genetics and Genomics.,40(8), 421-431 (2013)
  3. Floyd B.E., Morriss S.C., Macintosh G.C. and Bassham D.C., What to eat: evidence for selective autophagy in plants. Integr Plant Biol., 54(11), 907-20 (2012)
  4. Wu T.Y., Juan Y.T., Hsu Y.H., Wu S.H., Liao H.T., Fung R.W. and Charng Y.Y., Interplay between heat shock proteins HSP101 and HSA32 prolongs heat acclimation memory post transcriptionally in Arabidopsis, Plant Physiol.,161(4), 2075-84 (2013)
  5. Perez-Martin M, Perez-Perez M.E., Lemaire S.D. and Crespo J.L., Oxidative stress contributes to autophagy induction in response to endoplasmic reticulum stress in Chlamydomonas reinhardtii, Plant Physiol.,166(2), 997-1008 (2014)
  6. Perez-Perez M.E., Zaffagnini M., Marchand C.H., Crespo J.L. and Lemaire S.D., The yeast autophagy protease Atg4 is regulated by thioredoxin, Autophagy., 10(11), (2014)
  7. Minina E.A., Bozhkov P.V. and Hofius D., Autophagy as initiator or executioner of cell death, Trends Plant Sci.,(14), S1360-1385 (2014)
  8. Da Hora Junior B.T., Poloni J.F., Lopes M.A., Dias C.V., Gramacho K.P., Schuster I., Sabau X., Cascardo J.C., Mauro S.M., Gesteira A.S., Bonatto D. and Micheli F., Transcriptomics and systems biology analysis in identification of specific pathways involved in cacao resistance and susceptibility to witches' broom disease, Mol Biosyst.,8(5), 1507-19 (2012)
  9. De la Torre-Ruiz M.A., Pujol N. and Sundaram V. Coping with Oxidative Stress : The Yeast Model, Curr. Drug Targets,(2014)
  10. Iesmantavicius V., Weinert B. T. and Choudhary C. Convergence of ubiquitylation and phosphorylation signaling in rapamycin-treated yeast cells, Mol Cell Proteomics., 13(8), 1979-92 (2014)
  11. Umekawa M. and Klionsky D. J., The Cytoplasm-to-Vacuole Targeting Pathway : A Historical Perspective, Int. J. Cell Biol.,. 142634 (2012)
  12. Gordon B. S., Kazi A. A., Coleman C. S., Dennis M. D , Chau V., Jefferson L. S. and Kimball S. R., RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells, Cell Signal,26(3), 461-7 (2014)
  13. Morita M., Gravel S.P., Chenard V., Sikstrom K., Zheng L., Alain T., Gandin V., Avizonis D., Arguello M., Zakaria C., McLaughlan S., Nouet Y., Pause A., Pollak M., Gottlieb E., Larsson O., St-Pierre J., Topisirovic I. and Sonenberg N. mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation, Cell Metab, 18(5), 698-711 (2013)
  14. Lee D. Y. and Fiehn O. J., Metabolomic response of Chlamydomonas reinhardtii to the inhibition of target of rapamycin (TOR) by rapamycin, Microbiol Biotechnol., 23(7), 923-31 (2013)
  15. Cai Z., and Yan L. J., Rapamycin, Autophagy, and Alzheimer's Disease, J. Biochem Pharmacol Res. , 1(2),84-90 (2013)
  16. Wang K., Yang Z., Liu X., Mao K., Nair U. and Klionsky D. J., Phosphatidylinositol 4-kinases are required for autophagic membrane trafficking, J Biol Chem.,287(45), 37964-72 (2012)
  17. He S., O'Connell D., Zhang X., Yang Y., and Liang C., The intersection of Golgi-ER retrograde and autophagic trafficking, Autophagy,10(1), 180-1 (2014)
  18. Mao K., Chew L. H., Yip C. K. and Klionsky D. J., The role of Atg29 phosphorylation in PAS assembly, Autophagy, 9(12), 2178-9 (2013)
  19. Xia P., Wang S., Du Y., Zhao Z., Shi L., Sun L., Huang G., Ye B., Li C., Dai Z., Hou N., Cheng X., Sun Q., Li L., Yang X. and Fan Z., WASH inhibits autophagy through suppression of Beclin 1 ubiquitination, EMBO J.,32(20), 2685-96 (2013)
  20. Cheng S., Wu Y., Lu Q., Yan J., Zhang H. and Wang X., Autophagy genes coordinate with the class II PI/PtdIns 3-kinase PIKI-1 to regulate apoptotic cell clearance in C. elegans, Autophagy,29(12), 2022-32 (2013)
  21. Kruger F., Krebs M., Viotti C., Langhans M., Schumacher K. and Robinson D. G., PDMP induces rapid changes in vacuole morphology in Arabidopsis root cells, J Exp Bot.64(2), 529-40 (2013)
  22. Roy R., Kumar D., Chakraborty B., Chowdhury C., and Das P., Apoptotic and autophagic effects of Sesbania grandiflora flowers in human leukemic cells, PLoS One, 8(8), e71672 (2013)
  23. Li F., Chung T. and Vierstra R. D., AUTOPHAGY-RELATED11 plays a critical role in general autophagy and senescence-induced mitophagy in Arabidopsis, Plant Cell ., 26(2), 788-807 (2014)
  24. Jiang Q., Zhao L., Dai J. and Wu Q., Analysis of autophagy genes in microalgae: Chlorella as a potential model to study mechanism of autophagy, PLoS One, 7(7), e41826 ( 2012)
  25. Annibal A., Schubert K., Wagner U., Hoffmann R., Schiller J. and Fedorova M., New covalent modifications of phosphatidylethanolamine by alkanals: mass spectrometry based structural characterization and biological effects, J Mass Spectrom., 49(7), 557-69 (2014)
  26. Dooley H. C., Razi M., Polson H. E., Girardin S. E., Wilson M. I. and Tooze S. A., WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1, Mol Cell,55(2), 238-52 (2014)
  27. Vierstra R. D., The expanding universe of ubiquitin and ubiquitin-like modifiers, Plant Physiol., 160(1), 2-14 (2012)
  28. Bi F. C., Liu Z., Wu J. X., Liang H., Xi X. L., Fang C., Sun T. J., Yin J., Dai G. Y., Rong C., Greenberg J. T., Su W. W. and Yao, Loss of ceramide kinase in Arabidopsis impairs defenses and promotes ceramide accumulation and mitochondrial H2O2 bursts, N.Plant Cell, 26(8), 3449-67 (2014)
  29. Williams B., Verchot J. and Dickman M. B., When supply does not meet demand-ER stress and plant programmed cell death, Front Plant Sci., (5), 211 (2014)
  30. Olukolu B. A., Wang G. F., Vontimitta V., Venkata B. P., Marla S., Ji J., Gachomo E., Chu K., Negeri A., Benson J., Nelson R., Bradbury P., Nielsen D., Holland J. B., Balint-Kurti P. J., and Johal G. A., Genome-wide association study of the maize hypersensitive defense response identifies genes that cluster in related pathways, PLoS Genet., 10(8):e1004562 (2014)