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Antibacterial and Antifungal Activity of Crude Coconut Shell Oil

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Author Affiliations

  • 1Department of Chemistry, Kishinchand Chellaram College, Churchgate, Mumbai, 20, INDIA

Int. Res. J. Biological Sci., Volume 4, Issue (11), Pages 16-20, November,10 (2014)

Abstract

Traditionally coconut shell oil has been used for the treatment of skin infections. It has been used for antitumor, antihelminthic, antimicrobial, anti-inflammatory antiseptic and antioxidant activity. . The aim of the project was to extract oil from the coconut shell, purify it and test it for anti-bacterial and anti-fungal activity. The shell oil was first extracted by modified method then it was subjected to sequential solvent extraction with petroleum ether, chloroform and methanol. The anti-bacterial and anti-fungal activity was checked by ditch plate and agar cup diffusion method. The microbial activity was found to more active in Petroleum Ether extract, hence an attempt was made to separate the components present in it by Flash Column Chromatography. The monitoring was done with TLC, and pure components were further studied for identification of Functional groups present in it using FTIR.

References

  1. Zakaria Z.A., Reezal I., Mat Jais A.M., Somchit M.N., Sulaiman M.R., Marmin A.H.I., Sidek H., Husin S.H., Rahim M.H.A. and Abdul Rahman L., The antiinflammatory, anti-pyretic and wound healing activities of Cocos nucifera L. (MATAG types) fresh juice and kernel extract in experimental animals, Toxicol., 1, 516–526 (2006)
  2. Jean W.H. Yong, Liya Ge, Yan Fei Ng and Swee Ngin Tan, The Chemical Composition and Biological Properties of Coconut (Cocos nucifera Molecules, 14, doi:10.3390/molecules14125144
  3. Rajeev K Singla, Nitesh Jaiswal2, Varadaraj BhatHitesh Jagani, Antioxidant and Antimicrobial Activities of Cocos Nucifera Linn. (Arecaceae) Endocarp Extracts, Indoglobal Journal of Pharmaceutical Science361 (2011)
  4. Esquenazi D., Wagg M.D., Miranda M.M., Rodrigues H.M., Tostes J.B. and Rozental S., Antimicrobial and antiviral activities of polyphenolics from Cocos nucifera Linn, (Palmae) husk fiber extract, 647– 652 (2002)
  5. Chakraborty M. and Mitra A., The antioxidant and antimicrobial properties of the methanolic extract from Cocos nucifera mesocarp, (2008)
  6. Verma V, Bhardwah A, Rathi S and Raja R.BPotential Antimicrobial Agent from Cocos nucifera mesocarp extract; Development of a New Generation Antibiotic, Journal of Biological Sciences3202, 1(2), 48-54 (2012)
  7. A.R. Oyi, Onaolapoand J.A. and Obi R.C, Formulation and Antimicrobial studies of Coconut (Cocos nucifera Linne) oil, Research Journal of Applied Sciences Engineering and Technology, 2(2), 133-137 (2010)
  8. Deb Mandal M and Mandal S, Coconut (Cocos nucifera: Arecaeae): In health promotion and disease prevention, Asian Pacific journal of Tropic Medicine, 241-47 (2011)
  9. Satish Kolte; Application of HPLC and HPTLC in the study of some pharmaceutical products and study of biologically active compounds from crude coconut shell oil, 230 (1998)
  10. Shigwan A. and Gohil R., To study the role of coconut shells in mosquito repellent coils; Jigyaasa VIII; K. C. College church gate, Mumbai, India, (1998)