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Effects of Vitamins A,C and E on Growth and Colonial Morphology of Aspergillus flavus

Author Affiliations

  • 1Department of Biological Sciences, College of Science and Mathematics, MSU-Iligan Institute of Technology, Iligan City, PHILIPPINES

Int. Res. J. Biological Sci., Volume 3, Issue (10), Pages 52-59, October,10 (2014)


Contamination of the aflatoxin-producing Aspergellus flavus occurs in several economical significant crops causing decrease in crop yield and pose health problems. This study was designed to evaluate the ability of vitamins A, C, E, and its combinations to inhibit fungal growth with corresponding colonial morphology changes. This was done by adding a specific concentration of the different vitamins to a culture media and a single point inoculation was employed. It was then incubated for seven (7) days after which growth inhibition, total dry weights, and radial growth were obtained. Results of showed that both growth and mycelia biomass of A.flavus were affected by the vitamins used and its combinations. Among all the vitamins used, at higher concentrations, vitamin C (ascorbate) has complete inhibitory effects to the growth. Decreasing concentrations of thse vitamins in the medium led to an increasing amount of fungal growth as well as increasing fungal biomass and radial growth rates. It was observed that vitamin A, C, and E inhibit fungal growth in a similar way though its combinations exhibited lesser inhibitory effects. In addition, significant concentration-dependent inhibition of growth, mycelia biomass and radial growth rate was evident for selected vitamins. Thus, vitamins A, C, and E can be used to control fungal growth in important crops and processed agricultural products.


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