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Evaluation of Antibacterial Potential of Leaf extracts of Mimusops elengi

Author Affiliations

  • 1 Khallikote (Auto) College, Department of Botany and Biotechnology, Berhampur, Odisha, INDIA

Int. Res. J. Biological Sci., Volume 2, Issue (7), Pages 46-49, July,10 (2013)

Abstract

Different solvent extracts of the leaves of Mimusops elengi were prepared and screened for their antibacterial activity against six different bacterial strains including both gram negative strains such as Escherichia coli (MTCC 40), Pseudomonas aeruginosa (MTCC 424), Proteus vulgaris (MTCC 426) and gram positive strains such as Streptococcus pneumoniae (MTCC 237) and Staphylococcus aureus (MTCC 87), Staphylococcus epidermidis (MTCC 2639). The extracts were evaluated at 200 and 300mg/ml by using cup-plate method. All the tested extracts exhibited significant antibacterial activity in a dose dependent manner. Among the various extracts of Mimusops elengi leaves, methanol extract exhibited high inhibitory zone followed by ethanol, chloroform and petroleum ether. Petroleum ether extract was found to be ineffective at 200 mg/ml against all the test organisms. Thus, this in vitro study supports its traditional application as a preventive remedy for the treatment microbial diseases.

References

  1. Kirtikar K.R. and Basu B.D., Indian medicinal plants with illustrations, Uttaranchal, Oriental Enterprises, India, (2001)
  2. Shah P.J, Gandhi S.M., Shah B.M., Goswami S.S. and Santani D., Study of Mimosops elengibark in experimental gastric ulcers, J. Ethno. Pharmacol.,89, 305-311 (2003)
  3. Manjeshwar S.B., Ramakrishna J.P., Harshith P.B., Princy L.P. and Rekha B., Chemistryss and medicinal properties of the Bakul (Mimusops elengi Linn), A review. Food Res Int., 44, 1823-1829 (2011)
  4. Bharat G. and Parabia M.H.., Pharmacognostic evaluation of bark and seeds of Mimusops elengi L., IntJ Pharm Pharmaceut Sci., 110-113 (2010)
  5. Shanmugam S., Annadurai M. and Rajendran K., Ethnomedicinal plants used to cure diarrhoea and dysentery in Pachalur hills of Dindigul district in Tamil Nadu, Southern Ind J Appl Pharmac Sci., 94-97 (2011)
  6. Khare C.P., Encyclopedia of Indian medicinal plants, Springer Publication 314-315 (2004)
  7. Sakshi S, Vineet G, Rajiv G, Shubhini AS., Analgesic and antipyretic activity of Mimusops elengi L. (bakul) leaves, Pharmacologyonline,1-6 (2011)
  8. Wagner H, Bladt S, Zgainski EM.,Plant drug analysis. Berlin, Germany, Springer-Verlag, ( 1984)
  9. Abayasekara CL, Rangama BNLD, Panagoda GJ and Senanayake MRDM, Antimicrobial activity of Tephrosia purpurea (Linn.) Pers. And Mimusops elengi (Linn.) against some clinical bacterial isolates, J. Natn. Sci. Foundation Sri Lank., 37 (2),139-145 (2009)
  10. Gordon MC, David JN., Natural product drug discovery in the next millennium, Journal of Pharmaceutical Biology,39, 8-17 (2001)