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Evolutionary Analysis and Motif Discovery in Rhodopsin from Vertebrates

Author Affiliations

  • 1Department of Bioinformatics, Uttaranchal College of Science and Technology, Dehradun, INDIA
  • 2 Forest Pathology Division, Forest Research Institute, Dehradun, INDIA

Int. Res. J. Biological Sci., Volume 2, Issue (7), Pages 6-11, July,10 (2013)

Abstract

In the present investigation, total twenty different protein sequences of rhodopsin from different organisms of vertebrates were obtained from GenPept database and only 347 characters of each sequence were considered for motif discovery, motif family analysis and phylogenetic analysis. Three different motifs were discovered by MEME program. The Pfam analysis of these motifs result revealed that two motifs belonged to 7 transmembrane receptor family. Two major clusters of all retrieved sequences were obtained after phylogenetic analysis.

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