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Effect of the Aqueous Extract of Boerhavia Difusa Roots and Leaves of Hypoglycemic as well as Immuno Support Activity

Author Affiliations

  • 1 Dayanand PG College, Bachhrawan, Raebareli, INDIA

Int. Res. J. Biological Sci., Volume 1, Issue (6), Pages 62-65, October,10 (2012)

Abstract

Boerhavia diffusa (Family Nyctaginaceae) is a herbal plant, which is common in the tropics in both dry and rainy seasons. It is found in India and many other countries. In India it is found especially in swampy areas and commonly used as rabbit food by the local population. The herbalists, however, use the aqueous leaf extract to treat diabetes in man (unpublished data). The plant exhibits a somewhat periodic efficacy, with its maximum activity being noticed in the month of May. diffusa is used in traditional medicine for its anti-inflammatory, antibacterial and cardiotonic properties. It is used in the treatment of elephantiasis, night blindness and coneal ulcers.

References

  1. Agarwal R.R. and Dutt S.S. Chemical examination of Punarnava or Boerhaavia diffusa Linn, II. Isolation of an alkaloid punarnavine, Proc. Natl. Acad. Sci. United Provinces, Agra Audh. India, 5, 2402 (1935)
  2. Bagby G.C. Jr., Dinnarello C.A. and Wallac, P., et al., Interleukin 1 stimulates granulocyte macrophage colony-stimulating activity release by vascular endothelial cells, J. Clin. Invest., 78, 13161323 (1986)
  3. Bancroft J.D. and Cook H.F., Manual of Histologic Techniques. London: Churchill Livingstone, 171174 (1992)
  4. Barthwal M. and Srivastava K., Management of IUD-associated menorrhage in female rhesus monkeys (Macaca mulatta), Advances in Contraception, 7(1), 6776 (1991)
  5. Basu N.K., Lal S.B. and Sharma S.N., Investigations on Indian medicinal plants, Quart. J. Pharm. Pharmacol.,20, 3842 (1947)
  6. Chowdhury A. Boerhaavia diffusa, Effect on diuresis and some renal enzymes, Ann. Biochem. Exp. Med., 15, 11926 (1955)
  7. Orisakwe O.E., Affone O.J., Gamaniel K.S., Vongtau O.H. and Obi E., Hypoglycemic effect of the aqueous extract of Boerhaavia diffusa leaves, Indian J. Pharmacol., 33, 215216 (2001)
  8. Erah P.O., Osuide G.E. and Omogbai E.K.I., Hypoglycaemic effect of the extract of Solenostemon monostachys leaves, J West Afr Pharm,10, 21-7 (1996)
  9. Farjou I.B., Al-Ani M. and Guirgea S.Y., Lowering of blood glucose of diabetic rats by Artemisia extract, J Fac Med Baghdad,92, 137-41 (1987)
  10. Garg S., Proteins and free amino acid composition of certain Indian desert plants, I. Transactions of the Indian Society Desert Technology, University of Desert Studies, 3(1), 3134 (1978)
  11. I. Res. J. Biological Sci. International Science Congress Association 6511.Ikejima T.S., Okusawa P. and Ghezzi J.W., van der Meer, Dinarello C.A., Interleukin-induces tumor necrosis factor (TNF) in human peripheral blood mononuclear cells in in vitro and a circulating TNF- like activity in rabbits, J. Infect. Dis.,162, 21523 (1990)
  12. Immunomodulatory activities of Punarnavine 387 Ennist, D.L., Jones, K.H. Rapid method for identification of macrophages in suspension by acid alpha-naphthyl acetate esterase activity, J Histochem. Cytochem., 31, 9603 (1983)
  13. Jain S.P. and Singh S.C., Ethnomedical botancial survey of Ambikapur District, M.P. Ethnobiology in human welfare. Abstracts of the 4th International Congress of Ethnobiology, Lucknow, Uttar Pradesh, India, 17th-21st November, 293 (1994)
  14. Lamela M., Cadavid I., Gato A. and Calleja J.M., Effect of Lythrum saricaria in normoglycaemic rats, J Ethnopharm, 41 (1985)
  15. Lami N., Kadota S., Kikuchi T. and Momose Y., Constituents of the roots of Boerhaa6ia diffusa L. III. Identification of a Ca channel antagonistic compound from the methanol extract, Chemical and Pharmacological Bulletin, 39(6), 15511555 (1991)
  16. Liogier A., Plantas Medicinales de Puerto Rico y del Caribe. Iberoamerican de Ediciones Inc, San Juan, 123-127 (1990)
  17. Manu K.A. and Kuttan G. Effect of punarnavine, an alkaloid from Boerhaavia diffusa, on cell-mediated immune responses and TIMP-in B16F-10 metastatic melanoma bearing mice, Immunopharmacol, Immunotoxicol, 29, 569586 (2007)
  18. Manu K.A. and Kuttan G., Anti-metastatic potential of Punarnavine, an alkaloid from Boerhaavia diffusa, linn. Immunobiology, 214, 245255 (2009)
  19. Mishra J. and Singh R., The effect of indigenous drug Boerhaa6ia diffusa on kidney regeneration, Indian Journal of Pharmacology,12(1), 5964 (1980)
  20. Mule J.J., Marcus S.G., Yang J.C., Webber J.S. and Rosenberg S.A., Clinical applications of IL-6 in cancer therapy, Res. Immunol., 143, 777779 (1992)
  21. Oliver B., Oral hypoglycaemic plants in West Africa, J Ethnopharm, 2, 119-27 (1980)
  22. Rawat A.K.S., Mehrotra S., Tripathi S.K. and Shome U., Hepatoprotective activity of Punanarva - a popular ethnomedicine, Ethnobiology in human welfare, Abstracts of 4th International Congress of Ethnobiology, Lucknow, Uttar Pradesh, India, 17th-21st November, 100 (1994)
  23. Singh A., Singh R.G., Singh R.H., Mishra N. and Singh N., An experimental evaluation of possible teratogenic potential in Boerhaavia diffusa in Albino rats, Planta Medica, 57(4), 315316 (1991)
  24. Singh M.K., Usha S., Singh S.C. and Singh U., Phytoecological investigations of Boerhavia diffusa Linn of Darbhanga district, Bihar, Neo-Botanical, 2, 61-4 (1994)
  25. Singh V.K., Aggarwal S. and Gupta B.M., Immunomodulatory activity of Panax ginseng extract,Planta Med. 1984, 50, 462467. Jerne, N.K., Nordin, A.A. Plaque formation in agar by single antibody producing cells, Science, 140, 405408 (1963)
  26. Sredni B., Albeck M., Kazimirsky G. and Shalet F., Immunomodulator AS101 administered orally as a chemoprotective and radioprotective agent, Int. J. Immunopharmacol., 14, 613619 (1992)
  27. Steven A., Rosenberg D., Longo L. et al. In: Devita V.T., Jr., Hellmann S., Rosenberg S.A., Eds. Principles and Application of Biologic Therapy, 3012 (1985)
  28. Sumati S. and Zafar R. Genus Boerhaavia, Indian Natural Prod., 19, 310 (2003)
  29. Surange S.R. and Pendse G.S., Pharmacognostic study of roots of Boerhaavia diffusa Wild, (punarnava), J. Res. Indian Med., 7, 15 (1972)
  30. Szepesi G., J. Planar Chromatogr.-Mod. TLC 6 (1993) 187, USP XXV, Validation of Compendial Methods _1225_, The Pharmacopoeia of the United States of America, vol. XXV, United States Pharmacopoeial Convention Inc., Rockville, MD, 2256 2259 (2002)
  31. Trease G.E. and Evans W.C., Pharmacognosy, 12th edn. London Bailliere Tindall, 217-26 (1983)
  32. Van Snick J. Interleukin-6: an overview, Annu. Rev. Immunol., 8, 253278 (1990)
  33. Varley H., Gowenlock A.H., Bell M., Practical clinical biochemistry., 1, 389-91 (1991)
  34. WHO expert committee on diabetes mellitus, Technical Report Series No. 646 (1980)