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Comparative study of Withania somnifera and Ocimum sanctum for Anthelmintic Activity

Author Affiliations

  • 1 Dept. of Botany, Dr. H.S. Gour University, Sagar, MP, INDIA

Int. Res. J. Biological Sci., Volume 1, Issue (1), Pages 74-76, May,10 (2012)

Abstract

The hydroalcoholic extracts of Withania sominifera (Ws) and Ocimum sanctum (Os) were assayed against adult earthworms (Pheretima posthuma) for the evaluation of anthelmintic activity. Various concentrations of both extracts were tested and results were expressed in terms of time for paralysis and time for death of worms. Piperazine citrate (10 mg/ml) was used as a reference standard. The result showed that in both of the extracts (i.e. Os and Ws) dose of 40 mg/ml possesses more wormicidal activity. The time of paralysis was 2.5±0.6 and 2.8±0.8 whereas the time of death was 6.5±0.7and 7.1±0.9 in the case of Os and Ws respectively. The comparative study showed that out of the two, Os proves to be a better anthelmintic remedy.

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